Lei Shi Selected Research

Reactive Oxygen Species (Oxygen Radicals)

2/2024	Rational design of an iminocoumarin-based fluorescence probe for peroxynitrite with high signal-to-noise ratio.
10/2023	ROS-mediated Therapeutics Combined with Metal-based Porphyrin Nanoparticles and their Applications in Tumor Treatment.
1/2023	Single cell transcriptome profiling reveals cutaneous immune microenvironment remodeling by photodynamic therapy in photoaged skin.
1/2021	Tumor-Targeted Disruption of Lactate Transport with Reactivity-Reversible Nanocatalysts to Amplify Oxidative Damage.
5/2019	α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
1/2019	Matrine attenuates high-fat diet-induced in vivo and ox-LDL-induced in vitro vascular injury by regulating the PKCα/eNOS and PI3K/Akt/eNOS pathways.
11/2018	Zinc pthalocyanine-loaded chitosan/mPEG-PLA nanoparticles-mediated photodynamic therapy for the treatment of cutaneous squamous cell carcinoma.
12/2017	Leptin-induced migration and angiogenesis in rheumatoid arthritis is mediated by reactive oxygen species.
8/2017	Autophagic cell death induced by reactive oxygen species is involved in hyperthermic sensitization to ionizing radiation in human hepatocellular carcinoma cells.
10/2016	Physiological, genomic and transcriptional diversity in responses to boron deficiency in rapeseed genotypes.

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Lei Shi Research Topics

Disease

347	Neoplasms (Cancer) 05/2024 - 06/2008
70	Inflammation (Inflammations) 02/2024 - 03/2005
64	Infections 05/2024 - 01/2004
57	Neoplasm Metastasis (Metastasis) 03/2024 - 08/2009
52	Breast Neoplasms (Breast Cancer) 05/2024 - 06/2008
50	Carcinogenesis 05/2024 - 06/2008
44	Glioma (Gliomas) 12/2023 - 10/2008
32	Pain (Aches) 02/2024 - 05/2007
32	Wounds and Injuries (Trauma) 03/2023 - 08/2005
28	COVID-19 05/2024 - 01/2020
25	Glioblastoma (Glioblastoma Multiforme) 12/2022 - 09/2010
24	Hepatocellular Carcinoma (Hepatoma) 10/2023 - 11/2011
23	Nasopharyngeal Carcinoma 04/2024 - 06/2008
23	Fibrosis (Cirrhosis) 02/2024 - 07/2010
23	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2024 - 08/2009
22	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 11/2004
21	Lung Neoplasms (Lung Cancer) 11/2023 - 08/2009
20	Hypoxia (Hypoxemia) 01/2024 - 05/2011
20	Colorectal Neoplasms (Colorectal Cancer) 11/2023 - 01/2011
19	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2024 - 01/2013
15	Stroke (Strokes) 05/2024 - 10/2012
15	Colonic Neoplasms (Colon Cancer) 01/2024 - 04/2013
14	Melanoma (Melanoma, Malignant) 04/2024 - 04/2012
14	Atherosclerosis 11/2023 - 09/2010
13	Starvation 05/2024 - 10/2010
13	Multiple Myeloma 04/2024 - 10/2014
13	Prostatic Neoplasms (Prostate Cancer) 01/2024 - 10/2006
13	Body Weight (Weight, Body) 12/2023 - 01/2013
13	Hypertension (High Blood Pressure) 07/2021 - 05/2007
12	Stomach Neoplasms (Stomach Cancer) 05/2024 - 11/2011
12	Alzheimer Disease (Alzheimer's Disease) 03/2024 - 01/2009
12	Adenocarcinoma 01/2024 - 04/2008
12	Reperfusion Injury 12/2023 - 07/2005
12	Non-alcoholic Fatty Liver Disease 08/2023 - 08/2013
12	Hypersensitivity (Allergy) 01/2022 - 05/2011
11	Carcinoma (Carcinomatosis) 01/2024 - 04/2008
11	Pneumonia (Pneumonitis) 07/2023 - 12/2017
11	Urinary Bladder Neoplasms (Bladder Cancer) 06/2023 - 01/2007
11	Sepsis (Septicemia) 01/2023 - 08/2017
11	Leukemia 01/2023 - 02/2010
11	Hemorrhage 01/2023 - 05/2011
11	Virus Diseases (Viral Diseases) 01/2022 - 06/2004
10	Hepatitis B 10/2023 - 01/2015
10	Lymphatic Metastasis 09/2023 - 04/2008
9	Osteoporosis 05/2024 - 03/2011
9	Schizophrenia (Dementia Praecox) 04/2024 - 03/2013
9	Necrosis 01/2024 - 07/2016
9	Acne Vulgaris 12/2023 - 09/2020
9	Ulcerative Colitis 12/2023 - 08/2017

Drug/Important Bio-Agent (IBA)

137	Proteins (Proteins, Gene)FDA Link 05/2024 - 11/2004
52	Biomarkers (Surrogate Marker)IBA 03/2024 - 02/2009
52	MicroRNAs (MicroRNA)IBA 12/2023 - 10/2008
43	1-phenyl-3,3-dimethyltriazene (PDT)IBA 04/2024 - 07/2015
37	Long Noncoding RNAIBA 03/2024 - 01/2014
36	AcidsIBA 04/2024 - 03/2009
33	Messenger RNA (mRNA)IBA 04/2024 - 08/2006
30	CytokinesIBA 01/2024 - 01/2007
28	RNA (Ribonucleic Acid)IBA 04/2024 - 04/2013
25	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 11/2006
22	Interleukin-6 (Interleukin 6)IBA 01/2023 - 01/2011
21	VaccinesIBA 04/2024 - 11/2010
21	EnzymesIBA 01/2023 - 04/2008
18	Transcription Factors (Transcription Factor)IBA 04/2024 - 12/2007
18	LipidsIBA 12/2023 - 12/2007
17	Glucose (Dextrose)FDA LinkGeneric 05/2024 - 06/2008
17	LigandsIBA 04/2024 - 08/2009
17	InterleukinsIBA 01/2024 - 06/2013
17	Small Interfering RNA (siRNA)IBA 01/2024 - 12/2007
17	Therapeutic UsesIBA 01/2023 - 08/2013
16	Anti-Bacterial Agents (Antibiotics)IBA 12/2023 - 06/2015
16	AntigensIBA 08/2022 - 04/2008
15	CollagenIBA 01/2024 - 05/2002
15	Phosphotransferases (Kinase)IBA 10/2022 - 01/2013
14	Peptides (Polypeptides)IBA 03/2024 - 05/2008
14	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2024 - 11/2012
14	CateninsIBA 10/2023 - 06/2013
13	AntioxidantsIBA 12/2024 - 11/2015
13	Temozolomide (Temodar)FDA LinkGeneric 09/2022 - 09/2010
13	Interleukin-10 (Interleukin 10)IBA 07/2022 - 01/2011
11	Indicators and Reagents (Reagents)IBA 05/2024 - 02/2016
11	Immune Checkpoint InhibitorsIBA 01/2024 - 11/2018
11	C-Reactive ProteinIBA 01/2022 - 04/2012
10	Circular RNAIBA 04/2024 - 02/2020
10	Cisplatin (Platino)FDA LinkGeneric 01/2024 - 12/2013
10	Insulin (Novolin)FDA Link 12/2023 - 09/2008
10	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2023 - 07/2010
10	Antiviral Agents (Antivirals)IBA 01/2023 - 06/2004
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023 - 08/2006
10	AntibodiesIBA 01/2021 - 05/2012
9	ErbB Receptors (EGF Receptor)IBA 01/2024 - 12/2013
9	Hormones (Hormone)IBA 01/2024 - 01/2011
9	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2024 - 09/2014

Therapy/Procedure

168	Therapeutics 12/2024 - 01/2007
50	Drug Therapy (Chemotherapy) 05/2024 - 02/2010
44	Photochemotherapy (Photodynamic Therapy) 04/2024 - 01/2013
33	Immunotherapy 05/2024 - 05/2011
22	Radiotherapy 04/2024 - 06/2008
17	Lasers (Laser) 02/2024 - 05/2007
11	Aftercare (After-Treatment) 07/2023 - 09/2012
10	Ligation 01/2023 - 05/2007